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Updated: Jun 7, 2025

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
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Published on: February 3, 2023

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棕色脂肪组织热生成节奏是由SCN驱动的,独立于脂肪细胞时钟

Georgios K Paschos, Ronan Lordan, Taylor Hollingsworth

    bioRxiv : the preprint server for biology
    |November 18, 2024
    PubMed
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    上神核 (SCN) 通过同情信号传递控制棕色脂肪组织 (BAT) 热生成中的昼夜节律,独立于脂肪细胞钟. 这一发现对于理解能源消耗和肥胖至关重要.

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    The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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