人类GM-CSF/IL-3增强瘤免疫透在人性化HCC患者衍生异种移植中

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Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors
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Kelley Weinfurtner, David Tischfield, George McClung

    bioRxiv : the preprint server for biology
    |November 18, 2024
    PubMed
    概括

    这项研究开发了一种新的人性化小鼠模型,用于肝细胞癌 (HCC) 免疫治疗. 该模型增强了免疫细胞的透,提高了它对研究HCC瘤微环境和治疗反应的实用性.

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    Tumor Immunotherapy01:27

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    Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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