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Updated: Jun 7, 2025

Author Spotlight: Investigating the Motion Dynamics of the Eukaryotic Replisome Components at the Single-Molecule Level
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Published on: July 26, 2024

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在ORC缺陷细胞中,特定的来源选择和过度的功能MCM2-7负载

Yoshiyuki Shibata, Mihaela Peycheva, Etsuko Shibata

    bioRxiv : the preprint server for biology
    |November 18, 2024
    PubMed
    概括

    六个子单位的起源识别复合体 (ORC) 对DNA复制的起源规范或在人类癌细胞中进行MCM2-7加载并不重要. 特定的来源仍然被使用,过剩的MCM2-7被加载,即使没有ORC.

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