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相关概念视频

Kidney Structure01:45

Kidney Structure

57.8K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
57.8K
External Anatomy of the Kidney01:21

External Anatomy of the Kidney

5.0K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
5.0K
Internal Anatomy of the Kidney01:12

Internal Anatomy of the Kidney

8.8K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
8.8K

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相关实验视频

Updated: May 5, 2026

Optimization of Renal Organoid and Organotypic Culture for Vascularization, Extended Development, and Improved Microscopy Imaging
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Optimization of Renal Organoid and Organotypic Culture for Vascularization, Extended Development, and Improved Microscopy Imaging

Published on: March 28, 2020

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动态脏有机体微生理学分析平台

SoonGweon Hong1,2, Minsun Song1,2, Tomoya Miyoshi1

  • 1Division of Renal Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

bioRxiv : the preprint server for biology
|November 18, 2024
PubMed
概括
此摘要是机器生成的。

一个新的微生理学分析平台 (MAP) 改善了脏器官的发育和药物测试. 这项技术提高了可复制性和准确性,用于推进脏研究和精密医学.

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A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells
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A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells

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Efficient Vascularization of Kidney Organoids through Intracelomic Transplantation in Chicken Embryos
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相关实验视频

Last Updated: May 5, 2026

Optimization of Renal Organoid and Organotypic Culture for Vascularization, Extended Development, and Improved Microscopy Imaging
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Optimization of Renal Organoid and Organotypic Culture for Vascularization, Extended Development, and Improved Microscopy Imaging

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A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells
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A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells

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Efficient Vascularization of Kidney Organoids through Intracelomic Transplantation in Chicken Embryos
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科学领域:

  • 生物医学工程 生物医学工程
  • 再生医学是一种再生医学.
  • 药理学 药理学是指药理学的学科.

背景情况:

  • 器官提供了人类发育和疾病的模型,但面临着可复制性和准确性挑战.
  • 现有的模型限制了对脏片段和药物反应的详细分析.
  • 在生物科学和制药领域的先进应用需要提高有机体的效用.

研究的目的:

  • 引入一个动态脏器官微生理学分析平台 (MAP).
  • 提高器官的开发,建模和测试能力.
  • 扩大器官在生理学,病理学和制药研究中的实用性.

主要方法:

  • 在MAP中精确控制动态微环境.
  • 脏器官的小型化,用于详细的脏片段分析.
  • 应用MAP用于疾病建模和治疗探索.

主要成果:

  • MAP促进了高通量和可再生的人类脏器官的发展.
  • 对脏片段的增强分析有助于评估药物的毒性和安全性.
  • MAP有效地回顾了多囊性病的病理学,用于治疗测试.

结论:

  • 脏器官MAP增强了制药研究,标准化和分析.
  • 这个平台提升了有机体在生物学和精密医学中的质量和实用性.
  • 马普准备推进脏研究,药物开发和个性化治疗.