鉴定,量化和抗抑郁药类评估不同饮食果的富含安东素的提取物
Jun Wang1, Jie Cheng1, Ji-Xiao Zhu2
1Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering Huaqiao University Xiamen People's Republic of China.
Food science & nutrition
|November 18, 2024
概括
蓝和黑,富含特定的抗素,显示抗抑郁作用. 这些果减少压力激素和炎症,为心理健康治疗提供了潜力.
科学领域:
- 营养生物化学 营养生物化学
- 神经药理学神经药理学
- 食品科学 食品科学 食品科学
背景情况:
- 果因其高醇含量而闻名,特别是酸,与抗氧化剂和潜在抗抑郁药物相关.
- 安西安素,像氨基-3-银酸和氨基,是果中的关键生物活性化合物.
研究的目的:
- 为了识别和量化选定果中的安托西亚尼概况.
- 为了评估这些果的体内类似抗抑郁药的活性.
主要方法:
- 超高性能液体色谱-质谱学 (UPLC-MS) 用于安托素分析.
- 在小鼠体内研究,以评估果补充剂对压力荷尔蒙,神经递质,氧化应激和神经炎症的影响.
主要成果:
- 蓝和黑呈现出高水平的氨-3-银酸和氨.
- 急性果补充剂降低了血清皮质和增加了单胺神经递质.
- 慢性补充剂在小鼠中增加了抗氧化活性,并减少了海马神经炎症.
结论:
- 蓝和黑的神经化学,抗氧化和抗炎作用调解了它们的抗抑郁作用.
- 富含素-3-银酸和素的果显示出对功能性食物和精神健康补充剂的希望.
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