胃癌患者的转移模式和预后:基于监测,流行病学和最终结果的分析
Qiumei Dong1, Minqing Huang1, Xiaorong Lai1
1Department of Internal Medicine-Oncology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
Journal of gastrointestinal oncology
|November 18, 2024
概括
晚期胃癌患者通常有肝脏或肺部转移,这与比骨转移更好的生存率有关. 了解转移模式对于胃癌的预后至关重要.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 癌症研究 癌症研究
背景情况:
- 胃癌是主要的恶性瘤,经常在晚期被诊断出来.
- 转移性模式及其对晚期胃癌生存的影响需要进一步调查.
研究的目的:
- 为了研究胃癌患者的转移模式.
- 分析转移模式与生存结果之间的关联.
主要方法:
- 利用了来自监测,流行病学和最终结果 (SEER) 数据库 (2010-2015) 的数据.
- 采用了卡普兰-梅尔生存分析和考克斯比例回归模型.
- 分析了10262名转移胃癌的患者.
主要成果:
- 肝转移是最常见的单位转移 (32.72%).
- 单位转移的平均整体存活时间为4个月,多位转移的平均总存活时间为3个月.
- 只有肝脏和肺部的转移与只有骨头的转移相比,预后更好.
结论:
- 肝脏是胃癌转移最常见的地方.
- N阶段,化疗,手术和转移模式是独立的预后因素.
- 转移部位显著影响晚期胃癌的生存结果.
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