在患有急性胰腺炎的患者中,高血糖和巴尔哈萨尔分类的相关性
Guner Kilic1, Gulce Ecem Kilic2, Adnan Ozkahraman3
1Guner Kilic, Gastroenterology, Department of Internal Medicine, Van Training and Research Hospital, Van, Turkey.
Pakistan journal of medical sciences
|November 18, 2024
概括
高血糖水平和糖尿病 (DM) 加剧了急性胰腺炎 (AP) 的严重程度. 患有AP的糖尿病患者经历了明显更严重的结果,这表明血糖控制对AP管理至关重要.
科学领域:
- 内分泌学和新陈代谢学
- 胃肠病学和肝病学
- 临床医学 临床医学
背景情况:
- 在急性胰腺炎 (AP) 进展过程中葡萄糖水平升高会通过细胞因子释放加剧炎症.
- 高血糖和糖尿病 (DM) 对AP严重程度和临床过程的影响需要进一步调查.
研究的目的:
- 评估非糖尿病患者血糖水平对AP进展的影响.
- 评估糖尿病 (DM) 对急性胰腺炎 (AP) 严重程度和病程的影响.
主要方法:
- 在2014年至2018年期间,对343名入院患者进行了回顾性分析.
- 患者被分为糖尿病 (DM) 和非糖尿病组.
- 使用基于断层成像的修改巴尔塔扎尔分类来评估AP严重程度.
主要成果:
- 糖尿病组占患者的15.1% (n=52),而非糖尿病组占84.9% (n=291).
- 在非糖尿病组中,54.9%的血清葡萄糖<125 mg/dl,45.1%的血清葡萄糖>125 mg/dl.
- 根据修改的巴尔塔扎尔分类,严重的AP在糖尿病组显著高 (p<0.05).
结论:
- 高血糖在AP中很常见,并对疾病进展产生负面影响.
- 血糖水平升高与AP严重程度增加和愈合延迟有关.
- 糖尿病是严重急性胰腺炎的重要危险因素.
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