内镜下粘膜剖析对早期胃癌患者的胃肠功能和营养状况的影响
Qi-De Xu1, Hua Liu2, Hui-Wen Zhang3
1Department of Gastroenterology, Beijing No. 6 Hospital, Beijing 100007, China.
World journal of gastrointestinal oncology
|November 18, 2024
概括
与内镜粘膜下切除 (EMR) 相比,内镜粘膜下切除 (ESD) 在早期胃癌 (EGC) 患者中改善了胃肠功能和营养状况. 经过手术后,ESD提供了更好的恢复和营养水平.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 内镜手术 进行内镜手术
背景情况:
- 胃癌 (GC) 构成严重的全球健康威胁,影响患者的生存和预后.
- 早期胃癌 (EGC) 管理对于改善长期生存率至关重要.
研究的目的:
- 评估内镜下粘膜解剖 (ESD) 与内镜粘膜切除 (EMR) 对EGC患者胃肠功能和营养状况的影响.
- 为了比较EGC治疗的ESD和EMR之间的手术结果和并发症率.
主要方法:
- 一项涉及80名EGC患者的比较研究,分为ESD (n=42) 和EMR (n=38) 组.
- 对手术指数,病变切除率,术后胃肠道恢复,营养状况和并发症发生率的分析.
主要成果:
- ESD 显示出较高的病变切除率和更短的胃肠道通风时间.
- 接受ESD治疗的患者出现了术后营养标志物 (白蛋白,前白蛋白,血红蛋白,转移素) 的改善,以及有利的pepsinogen配置 (较高的PG I,较低的PG II).
- 虽然这两组都经历了营养状况的下降,但ESD组显示出更好的恢复. 没有观察到并发症发生率的显著差异.
结论:
- 内镜下粘膜切割 (ESD) 促进了EGC患者手术后胃肠功能更快地恢复.
- 在EGC患者中,ESD显著提高了术后营养水平.
- 在早期胃癌 (EGC) 管理中,ESD是一种可行的和有益的治疗选择.
相关概念视频
Endoscopic Procedures I: Esophagogastroduodenoscopy
69
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
69
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
82
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
82
Enteral Nutrition I: Orogastric and Nasogastric Feeding
202
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
202
Peptic Ulcer Disease V: Surgical Management and Nursing Care
231
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
231
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
51
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
51
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
319
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
319


