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D-Dimer/血小板比率预测急性型大动脉剖析患者的住院死亡
Ani Zhao1, Yanchun Peng2, Baolin Luo2
1School of Nursing, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
International journal of general medicine
|November 18, 2024
概括
D-二次数与血小板数比 (DPR) 可以预测急性A型大动脉剖析 (ATAAD) 患者的住院死亡. DPR升高是ATAAD患者死亡的独立风险因素.
科学领域:
- 心脏病学 心脏病学
- 血管外科 血管外科
- 临床病理学 临床病理学
背景情况:
- 急性A型大动脉解剖 (ATAAD) 是一种具有高死亡率的危急疾病.
- 确定ATAAD的预后指标对于患者管理至关重要.
- D-二聚体与血小板计数比率 (DPR) 已成为一种潜在的生物标志物.
研究的目的:
- 在急性A型大动脉解剖 (ATAAD) 患者中调查D-二聚体与血小板计数比率 (DPR) 的预后值.
- 确定DPR是否可以预测ATAAD患者的住院死亡率.
主要方法:
- 在2022年1月至2023年4月期间入院的197名ATAAD患者的回顾性分析.
- 患者被分为生存 (n=173) 和死亡 (n=24) 组.
- 使用后勤回归和ROC曲线分析来评估DPR和住院死亡之间的关系.
主要成果:
- 住院死亡率为12.2% (24人死亡).
- 死亡组的患者总胆红素,直接胆红素,间接胆红素,D-二次体,红细胞体积分布宽度和DPR水平显著更高.
- 多变量分析确定了DPR>0.0305ug/mL作为ATAAD患者死亡的独立风险因素.
结论:
- 增加的D-二聚体与血小板计数比率 (DPR) 与ATAAD患者的住院死亡有显著的相关性.
- DPR作为一个有价值的独立预后指标,用于ATAAD中的死亡率.
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