药剂师主导的干预措施在农村患者中识别和解决药物相关问题和潜在不适当的处方方面的影响:试点研究
Salvador Gutiérrez-Igual1,2,3, Rut Lucas-Domínguez4,5,6, José Sendra-Lillo1,2
1Muy Ilustre Colegio Oficial de Farmacéuticos de Valencia (MICOF), Valencia, Spain.
Exploratory research in clinical and social pharmacy
|November 18, 2024
概括
农村药房的药剂师主导的药物审查发现了许多与药物相关的问题 (DRP) 和可能不适当的处方 (PIP). 干预措施显著减少了这些问题,改善了患者的安全性,并防止了不良健康结果.
科学领域:
- 临床药房 临床药房
- 医疗保健服务研究 医疗服务研究
- 药物安全 药物安全
背景情况:
- 与毒品相关的问题 (DRP) 导致严重的发病率,死亡率和医疗保健费用.
- 农村地区在管理与药物有关的问题方面面临着独特的挑战.
- 临床药房服务,包括药物审查,提供潜在的解决方案.
研究的目的:
- 通过在农村药房使用新的软件,评估DRP和潜在不适当处方 (PIP) 的流行情况.
- 评估药剂师主导干预 (PLI) 在解决已识别的DRP和PIP方面的有效性.
主要方法:
- 在西班牙17家农村药房进行了为期6个月的前性多中心观察试点研究.
- 实施Revisem®,一种类型1药物审查软件,以检测DRP和PIP.
- 对135名多药患者的临床病史分析,比较PLI前后的DRP/PIP计数.
主要成果:
- 在135名患者中发现了1545个与药物相关的问题 (1166个DRP,379个PIP).
- 药物相互作用是最常见的问题 (43.7%).
- 每名患者的平均事件数量在PLI后显著下降,从9.7降至8.8 (p < 0.05).
结论:
- 药剂师主导的干预措施有效地检测到农村环境中大量的DRP和PIP.
- 这些干预措施显著减少了DRP和PIP的负担.
- 这种方法有望防止农村患者群体的负面健康结果.
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