大脑细胞tDCS增强了慢性失言症患者的功能性沟通技能
Ji Hyun Kim1, Sarah Cust1, Becky Lammers1
1Department of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD.
Aphasiology
|November 18, 2024
概括
超直流刺激 (tDCS) 改善了阿法西亚患者的定性沟通. 这种神经调节工具显示了增强慢性失言症中风幸存者的功能性沟通技能的潜力.
科学领域:
- 神经科学是一个神经科学.
- 语音和语言治疗治疗
背景情况:
- 跨直流刺激 (tDCS) 是一种潜在的神经调节方法,用于增强中风后失语症的语言治疗.
- 关于改善日常功能沟通的tDCS疗效的数据有限.
研究的目的:
- 评估小脑tDCS与计算机化失语治疗相结合是否能改善慢性失语患者的功能性沟通.
- 评估对特定通信维度和命名能力的影响.
主要方法:
- 一个随机的,双盲的,假冒控制的,主体内交叉研究,涉及28名参与者.
- 参与者接受了15次阳极或阴极大脑tDCS与计算机化失语治疗,其次是假治疗,或者反之亦然.
- 线性混合效应回归模型分析了美国语音语言听力协会对成人沟通技能的功能评估 (ASHA-FACS) 尺度 (沟通独立性和沟通的定性维度) 和命名能力的变化.
主要成果:
- 在通讯的整体质量维度 (QDC) 平均得分中观察到tDCS诱导的显著改善,但不是通讯独立性 (CI) 平均得分.
- 与假药相比,小脑刺激在治疗后立即,2周和2个月的随访中显示出对整体QDC平均得分的更高的有效性.
- 在tDCS条件下,ASHA-FACS CI平均变化和命名能力 (训练有素和未训练有素) 之间发现了显著的关联,但在假条件下没有.
结论:
- 脑膜tDCS,当与计算机化失语治疗相结合时,在慢性失语患者中增强功能性沟通的定性方面显示出初步承诺.
- 这些发现表明,tDCS作为一种可行的辅助疗法,可以改善沟通独立性和在失言症康复中整体沟通的有效性.
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