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在新辅助疗法后对T4低直肠癌进行腹腔切除 - - 结果是否可接受?

Devesh S Ballal¹, Prudvi Raj^2,3, M Janesh^2,3

¹Division of Colon and Rectal Surgery, Advocate Lutheran General Hospital, Park Ridge, IL USA.

Indian journal of surgical oncology

|November 18, 2024

概括

治疗后的MRI对于T4低直肠癌的手术规划是安全的. 这种方法不会对这些患者的病理或长期瘤结果产生负面影响.

科学领域:

结肠直肠外科手术是什么意思
瘤成像 - - 癌症成像
结直肠癌分期结直肠癌分期

背景情况:

在T4低直肠癌的手术规划中,对于使用治疗后MRI与治疗前MRI之间缺乏共识.
精确的分期和手术规划对于优化直肠癌的结果至关重要.

研究的目的:

确定在T4低直肠癌患者的手术规划中使用治疗后MRI的安全性和有效性.

主要方法:

一个前性维护的腹腔切除数据库的回顾性审查.
患者被分为临床T3 (A组) 和临床T4 (B组) 队列.
倾向匹配用于平衡基线特征;病理环切割边缘阳性是主要结果.

主要成果:

病理外围切除边缘的阳性率在各组之间是可比的 (11.9%对12.1%,p=0.951).
在单变量或多变量回归中,没有观察到小组对边缘阳性的显著影响.
无病生存率和总生存率在两组之间也相似.

结论:

治疗后的MRI可以安全地用于T4低直肠癌的手术规划.
使用响应MRI不会影响病理或长期瘤的结果.

关键词:

一年一度的年均价格响应MRI的MRI反应这是T4直肠癌.

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