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在低风险患者进行过导管或外科动脉置换后的十年后果:观察者研究

Fausto Biancari¹, Paola D'Errigo², Marco Barbanti^3,4

¹Department of Cardiovascular Surgery, Centro Cardiologico Monzino IRCCS, Milan, Italy.

International journal of cardiology. Heart & vasculature

|November 18, 2024

概括

在患有大动脉狭窄症的低风险患者中,透气管大动脉置换 (TAVR) 显示的10年生存率低于外科大动脉置换 (SAVR). 长期数据对比这些手术对大动脉狭窄仍然有限.

科学领域:

心血管医学心血管医学
干预心脏病学干预心脏病学
心脏外科手术心脏外科手术

背景情况:

对通过导管的大动脉置换 (TAVR) 与大动脉缩 (AS) 的外科大动脉置换 (SAVR) 的长期比较数据有限.
与SAVR相比,TAVR对AS的长期益处的证据很少.

研究的目的:

为了比较TAVR和SAVR之间的10年生存率和重复手术的需要,在AS的低风险患者中进行.
为了评估TAVR的长期结果,使用早期一代设备与SAVR相比.

主要方法:

来自前性观察性OBSERVANT研究的EuroSCORE II<4%的患者的分析.
倾向性得分匹配创造了355对TAVR和SAVR患者.
主要结局是10年生存期;次要结局是重复大动脉门手术.

主要成果:

在TAVR (2.5%) 和SAVR (2.8%) 之间30天死亡率没有显著差异.
与SAVR (37.0%) 相比,TAVR (18.2%) 后的十年生存率明显较低 (p < 0.001).
在手术后3年,生存率的差异变得显著;在重复手术中没有显著差异.

结论:

在低风险患者中,与SAVR相比,使用早期代假肢的TAVR与较低的10年生存率有关.
这些发现凸显了对使用较新的TAVR技术的长期结果进行进一步研究的需要.

关键词:

大动脉门狭窄症这就是SAVR的原因.在TAVRR中,我们可以看到.通过导管更换大动脉门.低风险的低风险是什么

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