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Updated: Jun 7, 2025

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

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通过NMR和分子模拟研究,通过C和F标签阐明安二B离子通道的结构

Yuichi Umegawa1, Hiroshi Tsuchikawa2,1, Wataru Shinoda3,4

  • 1Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan. yumegawa@chem.sci.osaka-u.ac.jp.

Organic & biomolecular chemistry
|November 18, 2024
PubMed
概括

氨酸B (AmB) 在真菌膜中与埃尔戈斯特 (Erg) 形成离子通道,这对其抗真菌活性至关重要. 研究人员使用同位素标记的AmB,固态NMR和模拟来阐明AmB-Erg通道结构.

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