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Updated: Jun 7, 2025

Study of Protein-protein Interactions in Autophagy Research
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PINK1通过调节外围管道结节来控制RTN3L介导的ER自

Ravi Chidambaram1, Kamal Kumar1, Smriti Parashar1

  • 1Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.

The Journal of cell biology
|November 18, 2024
PubMed
概括

帕金森病蛋白PINK1塑造了内质网膜 (ER),通过ER-phagy清除错误折叠的蛋白质. 失去PINK1会损害这个过程,但DRP1蛋白可以恢复它,这表明治疗潜力.

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