由于变暖而引起的感染外热生物的过度死亡率取决于病原体王国和进化史
Jingdi Li1,2, Nele Guttmann3,4, Georgia C Drew1,5
1Department of Biology, University of Oxford, Oxford, United Kingdom.
PLoS biology
|November 18, 2024
概括
气候变化增加了来自细菌感染的宿主死亡率,特别是新鲜的细菌感染. 病原体的毒性取决于进化史和温度,影响物种的生存.
科学领域:
- 生态生态学 生态生态学
- 进化生物学 进化生物学
- 气候变化科学 气候变化科学
背景情况:
- 气候变化推动了极端高温事件,增加了传染病风险和威胁物种.
- 温度升温和感染对宿主健康的综合影响尚不清楚.
研究的目的:
- 研究温度升温如何影响外热动物宿主死亡率和病原体毒性.
- 确定宿主病原体进化史和病原体类型在调节这些影响中的作用.
主要方法:
- 从101个外热动物宿主-病原体系统中对超过190个效应大小的元分析.
- 分析重点是细菌和真菌病原体,考虑既定和新型感染.
主要成果:
- 变暖显著增加了来自细菌感染的宿主死亡率.
- 已建立的细菌病原体在更高的温度下显示出更高的毒性.
- 新型感染在较低温度时更致命,病毒性随着温度差异越大而增加.
- 只有当温度接近其热量最佳时,真菌病原体的毒性才会增加.
- 影响独立于宿主生命阶段,免疫复杂性或实验方法.
结论:
- 变暖会以不同的方式改变病原体的毒性,这取决于病原体的类型和进化史.
- 了解这些模式对于预测全球变化对宿主-病原体动态和物种持久性的影响至关重要.
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