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在容易管的患者中确定与ERCP后胰腺炎相关的风险因素:一个前性的多中心观察研究 (带视频)
Kyong Joo Lee1, Eunae Cho2, Da Hae Park1
1Division of Gastroenterology, Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea.
Gastrointestinal endoscopy
|November 18, 2024
概括
在ERCP后的胰腺炎 (PEP) 即使是轻松的胆管管道也可能发生. 患有急性胰腺炎和急性胆道炎的病史是这些患者PEP的主要风险因素.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 胰腺学 胰腺学
背景情况:
- 困难的胆管通道是ERCP后胰腺炎 (PEP) 的已知危险因素.
- 有限的研究存在于PEP发病率和风险因素在容易管患者.
- 本研究通过在简单的ERCP程序的背景下调查PEP来弥补这一差距.
研究的目的:
- 为了确定PEP的发病率在接受容易胆道管治疗的患者中.
- 在这个特定的患者群体中确定与PEP相关的独立风险因素.
- 在ERCP期间评估其他与程序相关的不良事件 (AE).
主要方法:
- 接受ERCP的天真大乳头患者的潜在招募 (2018年6月 - 2023年6月).
- 主要终点:在易于取管的队列中PEP发生率.
- 二级终点:确定PEP风险因素和评估其他AE.
主要成果:
- 在1930名患者中,有1061人 (54.9%) 获得了轻松的管.
- 在轻松管组中,PEP发生率为3.0%.
- 确定了独立的PEP风险因素:急性胰腺炎史 (OR 6.75) 和入院时的急性胆道炎 (OR 2.25).
- 内镜缩切除术和胆管支架安置与其他AE相关.
结论:
- 评估患者和程序因素对于减轻PEP风险至关重要,即使在轻松的管病例中.
- 虽然PEP发病率很低,但严重的病例需要谨慎,特别是在以前患有胰腺炎或胆管炎的患者中.
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