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Updated: Jun 7, 2025

Transplantation of Human Stem Cell-Derived GABAergic Neurons into the Early Postnatal Mouse Hippocampus to Mitigate Neurodevelopmental Disorders
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人类多能干细胞衍生的海马体模型

Haruka Nishimura1, Yun Li1

  • 1Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

The international journal of biochemistry & cell biology
|November 18, 2024
PubMed
概括

人类多能干细胞 (hPSCs) 为研究人类海马提供了一种新的方法,这对记忆和导航至关重要. 本综述探讨了hPSC衍生的海马体模型,以了解发育和疾病.

关键词:
在海马体内,海马体人类多能干细胞是人类多能干细胞.在体外模型模型.神经发育障碍 神经发育障碍器官类动物 器官类动物

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EPS and iPS Cells in Disease Research01:21

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Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
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