在心力衰竭中,心率和氧气脉冲响应的预后值与左心室射出分数超过40的心力衰竭
Mika Tashiro1, Ayumi Goda2, Yoshiaki Yanagisawa1
1Department of Cardiovascular Medicine, Kyorin University Hospital, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
概括
在炼期间心率降低 (HR) 和中风体积增加 (SV) 的心力衰竭与保存的喷射分数 (HFpEF) 患者的预后不佳. 这突显了HFpEF中HR和SV联合限制的预后意义.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
- 心脏衰竭研究研究
背景情况:
- 心脏输出由心率 (HR) 和中风体积 (SV) 确定.
- 在心力衰竭中,保留射出分数 (HFpEF),运动期间有限的HR增加与不良的运动耐受性相关.
- 由于HR反应受损和HFpEF中补偿性SV变化的预后影响仍然不清楚.
研究的目的:
- 调查HFpEF患者运动期间心率 (HR) 和中风体积 (SV) 储备的联合限制对预后的影响.
- 为了确定心肺运动测试期间HR和SV反应之间的相互作用是否预测HFpEF中的心血管事件.
主要方法:
- 评估了129名住院的HF患者,在鼻节律中保留了喷射分数 (LVEF>40%).
- 评估心率储备 (HRR) 和O2脉冲储备 (SV储备的替代品) 使用心肺运动测试.
- 利用卡普兰-梅尔分析和考克斯比例危险模型来评估结果,平均随访时间为562天.
主要成果:
- 根据中位数HR储备和O2脉冲储备,患者被分为四组.
- 在HR储备受损和O2脉冲储备受损 (n=37) 的组中,心血管事件的发生率明显高于保留储备的组.
- 损坏的HR储备与保存的O2脉冲储备相结合,并没有显著影响预后.
结论:
- 运动期间心率和中风体积 (以O2脉冲表示) 的同时下降与HFpEF患者的预后明显差相关.
- 这一发现强调了在运动压力测试中评估心脏输出的两个组成部分对于高压力压力测试中的风险分层的重要性.
关键词:
长期不称职的不称职.运动测试 运动测试心脏衰竭是因为心脏衰竭.心率的心率的心率的心率的心率心率心率心率心率心率心率心率心率心率心率心率心率心率心率心率心心保存在的喷射分数.冲击体积的冲击体积是如何形成的更多相关视频
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