对量身定制的患者导航程序的评估,以改善多目标便DNA测试的坚持性.
Edward Cytryn1, Zachary Stauber1, Kayla Jaeckel2
1Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Journal of general internal medicine
|November 18, 2024
概括
量身定制的患者导航 (TPN) 通过多目标便DNA (mt-sDNA) 测试显著改善了结直肠癌查. TPN增加了测试完成率和减少了不可使用的样本,提高了查吸收率.
科学领域:
- 在瘤学瘤学.
- 预防医学 预防医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 多目标便DNA (mt-sDNA) 测试是结直肠癌查的非侵入性选择.
- 测试依从性仍然是一个挑战,可能会限制mt-sDNA查的影响.
- 量身定制的患者导航 (TPN) 在改善其他癌症查方法的遵守方面取得了成功.
研究的目的:
- 评估TPN在提高mt-sDNA测试完成率方面的有效性.
- 评估TPN是否可以减少无法处理 (SCNBP) 的样本率.
主要方法:
- 一项前性研究是在一个大型的城市学术初级保健诊所中进行的,该诊所为医疗脆弱的人群提供服务.
- 包括2022年 (预干预) 和2023年 (干预) 收到mt-sDNA订单的患者.
- 在12个月的干预期间,患者导航提供了TPN以支持测试完成.
主要成果:
- TPN与90天mt-sDNA完成率 (51%对39%) 的显着增加有关.
- 此外,TPN还导致SCNBP结果显著下降 (4%与5%相比).
- 尽管存在制造商导航服务,但这些改进仍被观察到.
结论:
- 量身定制的患者导航是通过mt-sDNA测试提高结直肠癌查采用率的有效策略.
- TPN提高了测试完成率和样本质量,使其成为预防性瘤学的宝贵工具.
- 研究结果表明,在mt-sDNA查计划中应考虑TPN,特别是在脆弱人群中.
相关概念视频
Serum Laboratory Studies, Stool Test, Breath Test
316
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
316
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
319
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
319


