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Updated: Jun 7, 2025

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一种苦的抗炎药物结合在人类苦味的两个不同的部位GPCR

Lior Peri1,2, Donna Matzov3, Dominic R Huxley4

  • 1The Institute of Biochemistry, Food Science and Nutrition, Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.

Nature communications
|November 18, 2024
PubMed
概括

研究人员确定了与药物结合的苦味受体TAS2R14的结构,揭示了独特的两部分结合机制. 这一发现促进了对苦味信号的理解,并有助于设计向化合物.

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