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Updated: Jun 7, 2025

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NOTCH3通过直接调节SPP1并激活PI3K/AKT通路来促进膀癌的恶性进展

Changxue Liu1, Huaixi Ge1, Chengquan Shen1

  • 1Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Cell death & disease
|November 18, 2024
PubMed
概括

缺口受体3 (NOTCH3) 通过升高分泌的蛋白1 (SPP1) 和激活PI3K/AKT通路来促进膀癌 (BLCA) 的进展. 向NOTCH3抑制BLCA生长和转移,提供了一个潜在的治疗策略.

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