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Updated: Jun 15, 2026

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成人灵长类动物中的海马神经发生:系统性审查

Thomas Elliott1, Kathy Y Liu2, Jemma Hazan2,3

  • 1East London NHS Foundation Trust, London, UK. thomas.elliott@nhs.net.

Molecular psychiatry
|November 18, 2024
PubMed
概括

新的神经元生成,或成人海马神经发生 (AHN),发生在成人灵长类动物,包括人类. 这个对记忆至关重要的过程随着年龄的增长而减弱,但在脑损伤后可能会增加.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...