评估土耳其人口中非常老年人 (≥80岁) 的组织病理学发现
Begüm Çalım-Gürbüz1, İrem Güvendir2, Müzeyyen Müge Savaş3
1Pathology Department, Basaksehir Cam and Sakura City Hospital, Basaksehir, Istanbul, 34480, Turkey. begumcalim@hotmail.com.
BMC geriatrics
|November 18, 2024
概括
对非常老 (≥80岁) 患者的病变组织病理学评估显示,大多数病例是良性病例. 然而,恶性病变仍然是一个重大问题,影响生活质量,需要谨慎管理.
科学领域:
- 老年医学 老年医学
- 病理学 病理学 病理学
- 在瘤学瘤学.
背景情况:
- 非常古老的人群中的病变具有不同的特征,需要进行基因病理学评估.
- 关于80岁及以上个体的病变组织病理特征的数据有限.
- 这项研究解决了在这个特定的人口群体中了解病变特征的需要.
研究的目的:
- 评估80岁及以上患者病变的组织病理特征.
- 在老年人群中对不同类型的病变的流行情况进行分类和分析.
- 为了解老年患者的病理诊断作出贡献.
主要方法:
- 对来自80岁以上患者的5376个病理样本进行了回顾性分析.
- 组织病理学诊断的分类为恶性 (MLs),良性/炎症性 (BLs) 和失生性-失形性/非侵入性恶性 (DLs) 病变.
- 使用Pearson的奇平方和费舍尔精确测试 (p<0.05显著性) 的统计分析.
主要成果:
- 大多数病变 (62%) 是良性/炎症性 (BLs),女性患病率更高.
- 恶性病变 (MLs) 在乳腺活检中更常见.
- 在细胞学样本中没有发现异形性/非侵入性恶性病变 (DLs).
结论:
- 虽然良性病变在非常老年人中最常见,但缺血性和恶性病变是显著的,并影响生活质量.
- 增加医疗保健访问可能有助于在这个年龄组中更高地检测良性病变.
- 这项研究增强了对老年人组织病理学诊断和样本管理的理解.
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