相关实验视频
Updated: Jun 7, 2025
04:23
The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
Published on: February 21, 2025
241
在患有青少年异常性关节炎的年轻成年人中,与肉类相关的因素:一个横截面研究
Myroslava Kulyk1, Marta Dzhus2,3
1Internal Medicine Department No 2, Bogomolets National Medical University, 13 Shevchenko boulevard, Kyiv, 03055, Ukraine. myroslavakulyk@gmail.com.
BMC musculoskeletal disorders
|November 19, 2024
概括
萨尔科佩尼亚是一种肌肉损失状况,影响了超过一半患有青少年异常性关节炎 (JIA) 的年轻成年人. 较高的疾病活性和关节损伤是JIA患者这种疾病的关键风险因素.
科学领域:
- 类风湿病学 类风湿病学
- 老年学是指老年学的学科.
- 肌肉骨健康 肌肉骨健康
背景情况:
- 标志着肌肉质量和力量的损失的萨尔科佩尼亚是老龄化人口的一个重大问题.
- 关于被诊断患有青少年异常性关节炎 (JIA) 的年轻成年人中肉类的患病率和危险因素的数据有限.
研究的目的:
- 为了确定JIA的年轻成年人中肉类的患病率.
- 在这个人口群体中识别与肉类相关的危险因素.
主要方法:
- 进行了一项涉及70名患有JIA的年轻成年人的横截面研究.
- 使用Find-Assess-Confirm-Severity算法诊断了萨科佩尼亚,包括手握强度,双能X射线吸收度和步行速度.
- 后勤回归分析确定了相关的风险因素.
主要成果:
- 在59%的患有JIA的年轻成年人中,肉类是普遍存在的,34%的人患有严重的肉类.
- 较高的疾病活性 (DAS28-ESR,cJADAS27),关节损伤 (JADI-A,JADI-E) 和较低的功能能力 (健康评估问卷) 是重要的预测因素.
- 与女性相比,男性的肌肉质量损失较低.
结论:
- 萨科佩尼亚是患有JIA的年轻成年人常见的疾病.
- 疾病活动,关节损伤和功能能力下降是导致JIA患者发生沙症的重要危险因素.
- 早期识别和管理这些因素对于减轻不良结果至关重要.
相关概念视频
01:09Changes in the Appendicular Skeleton with Age
1.8K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
1.8K
01:29Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
01:28Disorders of the Skeletal Muscle
887
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
887
01:19The Effect of Aging on Tissues
2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
01:27Growth of Cartilage and Bone Tissue
3.1K
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
3.1K
01:18Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K