在健康和全身性疾病中的冠状血管性指数:系统性审查
Mehrdad Motamed Shariati1, Sahel Khazaei2, Mariye Yaghoobi1
1Eye Research Center, Khatam Al-Anbia Eye Hospital, Mashhad University of Medical Sciences, Gharani Boulevard, Mashhad, Iran.
International journal of retina and vitreous
|November 19, 2024
概括
胸腔血管度指数 (CVI) 反映了各种系统性疾病的变化. 减少CVI与糖尿病视网膜病变,自身免疫性疾病和神经退行性疾病有关,显示出作为疾病生物标志物的潜力.
科学领域:
- 眼科医生 眼科 眼科
- 心血管研究研究心血管研究
- 神经学 神经学
背景情况:
- 状腺的血管性至关重要,受到全身健康的影响.
- 增强的深度光学连贯性断层扫描有助于胆道评估.
- 胸腔血管度指数 (CVI) 量化了胸腔血管结构的非侵入性.
研究的目的:
- 系统地审查当前关于全身状况下胆管血管度指数变化的研究.
- 总结关于CVI作为疾病进展的潜在生物标志物的发现.
主要方法:
- 系统性文献审查于2023年10月1日进行.
- 搜索的数据库是:MEDLINE (PubMed) 和Scopus. 这两种数据库.
- 对48项研究的定性评估,重点关注CVI和胸腔厚度.
主要成果:
- 包括48项研究,涵盖糖尿病,中枢神经系统,心血管,自身免疫和传染病.
- 在糖尿病视网膜病变,自身免疫性疾病和神经退行性疾病中观察到减少的CVI.
- CVI变化与全身性疾病严重程度相关,这表明生物标志物的潜力.
结论:
- 胸腔血管度指数的变化与影响血液动力学的系统性疾病有显著的相关性.
- CVI提供了对病理生理机制的洞察力,并且作为早期检测生物标志物显示出希望.
- 需要进一步的研究来评估CVI的临床效用和局限性.
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