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Updated: Jun 7, 2025

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
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Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

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当普通微分方程无法实现时,信号通路的动态建模

Timo Rachel1,2, Eva Brombacher1,3,4,5, Svenja Wöhrle4,6

  • 1Institute of Medical Biometry and Statistics, Medical Center, Faculty of Medicine, University of Freiburg, Stefan-Meier-Str. 26, Freiburg, Baden-Württemberg, 79104, Germany.

Bioinformatics (Oxford, England)
|November 19, 2024
PubMed
概括

我们扩展了延迟瞬态函数 (RTF) 方法,以建模剂量依赖的细胞信号传递动态. 这种方法为预测时间和度依赖反应提供了直观的参数,克服了普通微分方程模型的局限性.

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A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds

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