时间和头痛:对初级头痛疾病的时间过程的洞察力,用于诊断,潜在的病理生理学和治疗影响
Alicia Gonzalez-Martinez1,2, Jason C Ray3,4,5, Faraidoon Haghdoost6
1Department of Neurology, Hospital Universitario de la Princesa, Madrid, Spain.
Cephalalgia : an international journal of headache
|November 19, 2024
概括
时间是头痛疾病的关键. 本综述探讨了偏头痛,张力头痛和集群头痛的时间模式,有助于诊断和治疗.
科学领域:
- 神经学 神经学
- 时间生物学 时间生物学
- 头痛 医学 医学 医学
背景情况:
- 时间模式对于诊断头痛障碍和理解其潜在的病理生理学至关重要.
- 分析与时间相关的方面,可以深入了解初级头痛疾病的机制.
研究的目的:
- 审查关于初级头痛疾病时机的研究,包括攻击呈现和疾病演变.
- 为了将时间特征与偏头痛,紧张型头痛和集群头痛的病理生理学相关联.
主要方法:
- 使用Ovid MEDLINE和PubMed (1946-2023) 进行了全面的文献搜索.
- 国际头痛疾病分类,第三版,指导了对主要头痛疾病的审查.
主要成果:
- 偏头痛发作显示与荷尔蒙和下丘脑激活相关的昼夜和红外节律.
- 集群头痛具有环年性模式,夜间发作和下丘脑参与.
- 紧张型头痛缺乏明确的时代生物学模式;发病年龄在偏头痛中达到顶峰,头痛特征通常会随着时间的推移而减少.
结论:
- 时间模式对于表型和管理初级头痛疾病至关重要.
- 了解时间方面为推进和个性化头痛治疗提供了新的策略.
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