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Updated: Jun 7, 2025

Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System
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Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System

Published on: May 1, 2019

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简化了单克隆抗体的澄清和捕获过程,使用流化床离心法和用膜吸附剂进行多列染色法

Fabian Schmitz1,2, Martin Saballus2, Thomas Kruse2

  • 1Biothermodynamics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany.

Biotechnology and bioengineering
|November 19, 2024
PubMed
概括

这项研究引入了用于连续单克隆抗体 (mAb) 制造的简化澄清和捕获 (S-CC) 过程. 这种创新方法通过协调下游单位运营,显著提高生产率并降低成本.

关键词:
流化床离心法 流化床离心法整合过程是一个集成的过程.单克隆抗体净化净化方法多列色谱是多列色谱的一种方法.过程强化,过程强化.

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