血液透析开始后心血管事件的风险:一个自我控制的案例系列研究研究
Minyoul Baik1, Jimin Jeon1, Joonsang Yoo1
1Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.
Kidney research and clinical practice
|November 19, 2024
概括
开始血液透析 (HD) 在慢性病 (CKD) 患者中显著增加心血管疾病 (CVD) 风险,特别是在前10天内. 对于需要HD的CKD患者来说,仔细评估心血管疾病风险至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 患有慢性病 (CKD) 的患者面临心血管疾病 (CVD) 的风险增加.
- 在慢性病患者中,启动血液透析 (HD) 和随后的心血管疾病风险之间的关联需要彻底调查.
研究的目的:
- 评估慢性脏病 (CKD) 患者血液透析启动与心血管疾病 (CVD) 风险之间的关联.
主要方法:
- 一个自我控制的病例系列设计利用了全国性的韩国健康索赔数据库.
- 包括从2007年至2019年期间发病的CKD患者,以及从2008年至2020年期间发生的CVD事件 (中风,心肌梗塞).
- 风险时期与HD发病相对定义,年龄调整的发病率比率 (IRR) 根据基线计算.
主要成果:
- 在74,584名发生性HD的CKD患者中,12875人经历了心血管疾病.
- 心血管疾病风险在HD发病后升高,在最初的10天内达到顶峰 (IRR2.95).
- 缺血性中风和心脏病发作风险在1-2个月后降低,但出血性中风风险在5个月内仍然较高.
结论:
- 开始血液透析与慢性病患者心血管疾病风险增加有关.
- 对于患有HD的CKD患者来说,仔细评估心血管疾病风险至关重要.
- 心血管疾病风险的时间模式因HD发病后的中风类型而异.
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