一项研究评估益生菌在过敏性鼻炎中的作用
Monica Manhas1, Gopika Kalsotra2, Vaibhav Saini2
1Post Graduate Department of Physiology, GMC, Jammu, India.
概括
益生菌可以改善过敏性鼻炎的症状,当添加到标准治疗. 这项研究发现,在接受益生菌与抗胰岛素药物和类固醇一起服用的患者中,鼻腔症状得分显著降低.
科学领域:
- 免疫学 免疫学 免疫学
- 微生物组研究的研究.
- 过敏治疗 过敏治疗
背景情况:
- 过敏性鼻炎显著影响生活质量.
- 目前的治疗方法包括抗组胺剂和局部类固醇.
- 益生菌在过敏性鼻炎管理中的作用正在研究中.
研究的目的:
- 评估益生菌作为过敏性鼻炎的补充疗法的疗效.
- 为了比较过敏性鼻炎患者的治疗结果,有或没有益生菌补充剂.
- 评估益生菌对全鼻症状评分 (TNSS) 的影响.
主要方法:
- 一项随机对照研究涉及106名过敏性鼻炎患者.
- 患者被分为两组:益生菌加标准治疗 (A组) 和单独标准治疗 (B组).
- 总鼻腔症状评分 (TNSS) 测量在治疗前8周和治疗后8周.
主要成果:
- 组A (益生菌+标准治疗) 与组B (仅标准治疗) 相比,TNSS的统计显著减少.
- 治疗后的TNSS平均值在A组 (0.887 ± 0.776) 显著低于B组 (1.89 ± 0.776) (p < 0.05).
- 益生菌补充剂在改善过敏鼻炎症状方面表现出有效性.
结论:
- 益生菌可能是管理过敏性鼻炎的潜在补充策略.
- 益生菌补充似乎有效改善过敏性鼻炎症状和生活质量.
- 需要进一步的临床和分子研究来阐明在过敏性鼻炎中益生菌作用的机制.
相关概念视频
Allergic Reactions
27.2K
Overview
27.2K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
237
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
237
Drugs Used in Lower Respiratory Disorders: Overview
353
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
353
Microorganisms in Medicine and Therapeutics
1
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1
The Roles of Bacteria and Fungi in Plant Nutrition
35.1K
Plants have the impressive ability to create their own food through photosynthesis. However, plants often require assistance from organisms in the soil to acquire the nutrients they need to function correctly. Both bacteria and fungi have evolved symbiotic relationships with plants that help the species to thrive in a wide variety of environments.
35.1K
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K


