相关实验视频

Updated: Jun 7, 2025

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 25, 2016

内血小板丰富等离子疗法治疗突然的感觉神经听力损失:初步前性研究

Suktara Sharma¹, Vaibhav B Patel¹, Yashwant B Chhatbar¹

¹MS Otolaryngology, GCS Medical College & Research Centre, H-101, Red Avenue Maple County 2, Off Sindhu Bhavan Road, Ahmedabad, Thaltej, Gujarat 380058 India.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

|November 19, 2024

概括

内血小板丰富血 (PRP) 为突然感觉神经听力损失 (SSNHL) 患者提供了希望,这些患者对标准护理没有反应. 这种救援疗法显示出显著的听力改善和耳缓解,风险最小.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
再生医学是一种再生医学.
听力学听力学是指听力学.

背景情况:

突然的感觉神经听力损失 (SSNHL) 是一个重大的临床挑战,有效的救援治疗方法有限.
对于SSNHL的传统疗法往往产生不理想的结果,需要新的治疗方法.

研究的目的:

评估内血小板富血 (PRP) 作为常规疗法耐受性SSNHL患者的救援治疗的疗效.
评估自主PRP注射后的听力改善和主观耳变化.

主要方法:

一项前性研究涉及56名单边SSNHL患者,他们接受了两次自身PRP的入耳内注射.
在治疗前和治疗后一个月,听力值被听力测量评估.
还收集了患者报告的耳结局.

主要成果:

在PRP治疗后观察到显著的平均听力增长11.99dB,特别是在较低的频率 (高达13.88dB).
即使在氨基糖化物诱导的听力损失和症状持续时间延长的情况下,也注意到了积极的结果.
17名患者中有8名报告主观耳改善,没有严重的不良事件.

结论:

内PRP显示出作为SSNHL有效的救援疗法的潜力,特别是当初级治疗失败时.
需要进一步进行大规模的比较研究,以确定PRP在SSNHL管理中的作用及其长期疗效.
对于与SSNHL相关的耳,PRP的潜在益处需要进一步调查.

关键词:

内注射内注射内注射富有血小板血的血.突然的感官神经神经听力损失.单边听力损失是一种单边的听力损失.

更多相关视频

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

Published on: March 16, 2018

A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus

A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus

Published on: February 27, 2018

相关概念视频

Formation of the Platelet Plug

Formation of the Platelet Plug

The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...