热波和Pennes在人体皮肤中的生物热传递模型:一个短暂的比较分析
Zerin Jahan Tasnim1, R Nasrin1
1Department of Mathematics, Bangladesh University of Engineering and Technology, Dhaka, 1000, Bangladesh.
Heliyon
|November 19, 2024
概括
热波生物热模型 (TWMBT) 在人类皮肤中提供比Pennes更现实的短期热传递预测.
科学领域:
- 生物医学工程 生物医学工程
- 热物理 热物理
- 计算建模 计算建模
背景情况:
- 对人体皮肤进行精确的热建模对于诸如高热治疗和热诊断等应用至关重要.
- 经典的生物热传递模型可能无法完全捕捉短暂的热反应,特别是在微波暴露下.
- 了解微波诱导的热效应需要比较不同的生物热传递模型.
研究的目的:
- 用热波生物热传递模型 (TWMBT) 和Pennes生物热传递模型对多层人体皮肤的热传递进行比较分析.
- 研究微波功率和电磁频率对皮肤温度预测的影响.
- 评估TWMBT与Pennes模型对短暂加热场景的准确性和适用性.
主要方法:
- 开发一个2D多层人体皮肤模型 (表皮,皮肤,皮下皮肤,内细胞).
- 应用有限元法 (FEM) 来解决合的电磁波频率和生物热方程.
- 模拟微波功率 (4-16 W),频率 (0.9-4 GHz) 和暴露时间 (0-180 秒).
主要成果:
- 潘尼斯的模型预测的温度高于TWMBT.
- 在模型之间观察到显著的温度演变差异,特别是在高频短暂加热中.
- TWMBT证明了传热延迟,捕捉了Pennes模型错过的短期热行为.
结论:
- 与Pennes模型相比,TWMBT提供了更现实的短期热行为洞察力.
- 模型选择对于生物医学应用中的精确热分析至关重要.
- TWMBT有可能提高临床热疗法的准确性.
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