在选择的资源有限的初级医疗保健设施中,使用低至中等成本的实地测试数字技术进行药品质量评估
Kwabena Fm Opuni1, Gifty Sunkwa-Mills2, Maxwell A Antwi2
1Department of Pharmaceutical Chemistry, School of Pharmacy, University of Ghana, Legon, Ghana.
Digital health
|November 19, 2024
概括
数字技术在资源有限的环境中有效评估药品质量. 虽然查工具显示出前景,但药典测试显示了一些必需药物的质量差距.
科学领域:
- 制药科学 制药科学
- 公共卫生 公共卫生
- 医疗信息学 医疗信息学
背景情况:
- 数字技术为资源有限的医疗保健机构及时评估药品质量提供了机会.
- 确保药品质量对于有效的医疗保健服务至关重要,尤其是在资源有限的地区.
研究的目的:
- 评估精选的非传染性疾病药物,抗疟疾药物,抗生素,NSAIDs和血液药物的质量.
- 通过药品质量评估,评估数字制药供应链管理系统 (Med4All) 的潜力.
主要方法:
- 药物使用现场技术进行了选:TruScan分析仪和GPHF-minilab.
- 一组药物的子集使用药典黄金标准方法进行了质量确定.
- 对选方法与药典标准进行了对比分析.
主要成果:
- 南部/中部部门药品供应率超过90%,北方部门药品供应率达到64%.
- 在TruScan Raman (87%) 和GPHF-minilab (88%) 中,通过率很高,两者之间没有显著差异.
- 药典检测显示,24%的样本失败,包括迪克洛菲纳克,阿齐思罗米辛和 Glibenclamide.
结论:
- 像TruScan和GPHF-minilab这样的数字工具在评估初级医疗保健中的药品质量方面具有实用性.
- 尽管查结果很有希望,但药典测试发现了具有质量问题的特定药物,突出了当前的挑战.
- 这项研究为资源有限的环境中药品质量提供了宝贵的见解,为潜在的数字供应链整合提供了信息.
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