医院前静脉输液对严重创伤患者生理参数的影响
Hirofumi Mishima1,2, Koshi Nakagawa3, Hidekazu Takeuchi1,4
1Graduate School of Emergency Medical System, Kokushikan University, Tokyo, JPN.
Cureus
|November 19, 2024
概括
医院前对创伤患者进行静脉注射 (IV) 冲击并没有显著改变冲击指数. 然而,紧急救生技术人员 (ELST) 的静脉输入与缩血压显著增加有关.
科学领域:
- 紧急医疗 紧急医疗
- 创伤护理 创伤护理
- 生理学 生理学 生理学
背景情况:
- 医院前静脉注射 (IV) 输液由紧急救生技术人员 (ELST) 给处于休克状态的创伤患者.
- 这些静脉注射在医院入院前对生命体征变异性的影响尚不清楚.
- 日本在2014年批准了乳酸林格溶液IV的ELST用于特定的冲击条件.
研究的目的:
- 为了研究ELST在创伤患者中进行的医院前静脉输注对创伤患者遭受冲击的影响.
- 分析静脉注射后在医院前环境中对冲击指数和其他生理参数的变化.
- 确定医院前输液接入与静脉血压,心率和呼吸率变化之间的关联.
主要方法:
- 使用日本创伤数据库 (2019-2021) 进行回顾性队列研究.
- 患者分为IV接入 (+) 和IV接入 (-) 组.
- 用于估计治疗效果的倾向性得分匹配;主要终点是三角冲击指数 (DSI),次要终点包括静缩血压 (sBP),心率 (HR) 和呼吸率 (RR).
主要成果:
- 分析包括19793名患者,其中778名匹配对进行比较.
- 医院前IV接入与三角洲冲击指数 (DSI) 或心率 (HR) 的变化没有显著关联.
- 静脉输入显示出与缩血压 (sBP) 的增加有显著的关联,尽管效果大小小小.
结论:
- 通过ELSTs进行的医院前IV输注与创伤患者的冲击指数变化没有直接联系.
- 在前医院环境中,静脉输入与静脉压升高有显著的关联.
- 建议进一步研究包括IV液体体积,以充分理解这些发现.
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