体重不足作为主要腹部内恶性瘤手术的危险因素
Jia Yin Lim1, Yuhe Ke1, Nian Chih Hwang1
1Division of Anaesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore, SGP.
Cureus
|November 19, 2024
概括
接受重大腹部癌症手术的体重不足患者面临更高的风险,包括增加一年死亡率,重症监护室入院和更长的住院时间. 低体重指数 (BMI) 是激进癌症手术中不良结果的独立风险因素.
科学领域:
- 在瘤学瘤学.
- 外科手术的结果
- 营养科学 营养科学
背景情况:
- 亚洲瘤患者的身体质量指数 (BMI) 和术后结果之间的关联受到辩论.
- 虽然过度肥胖通常与癌症存活率降低有关,但一些研究表明,超重或肥胖状态可能会改善结果.
- 这项研究探讨了这样一个假设:更好的营养和热量储备在激进的癌症治疗中提供了生存优势.
研究的目的:
- 为了检查BMI与经过癌症手术的亚洲人群中手术后30天和一年的死亡率之间的关系.
- 评估BMI对重症监护室 (ICU) 入院率和住院时间的影响.
主要方法:
- 对646名经历了重大腹部癌症手术的亚洲患者进行了回顾性审查.
- 患者被分为体重不足 (BMI < 18.5 kg/m2),体重正常 (BMI 18.5-27.5 kg/m2) 和肥胖 (BMI > 27.5 kg/m2) 的两组.
- 分析的结果包括30天和一年的死亡率,ICU入院和住院时间.
主要成果:
- 体重不足患者的30天死亡率为8%,而正常BMI为1%和肥胖患者为3%.
- 在体重不足组 (53%) 的1年死亡率明显高于正常 (14%) 和肥胖 (12%) 组 (p < 0.001).
- 体重不足的患者增加了ICU入院率 (25%对正常和肥胖患者的6%) 和更长的住院时间.
结论:
- 体重不足与增加一年死亡率,更高的ICU入院率和术后长时间住院相关.
- 低BMI被认为是亚洲人群中重大激进手术的独立风险因素.
- 研究结果强调了营养状况在癌症患者手术结果中的关键作用.
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