Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

11.1K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
11.1K
Nucleic Acid Structure01:25

Nucleic Acid Structure

6.0K
The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
DNA Structure
DNA...
6.0K
DNA Microarrays02:34

DNA Microarrays

17.2K
Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
17.2K
DNA Base Pairing02:27

DNA Base Pairing

26.9K
26.9K
DNA as a Genetic Template02:05

DNA as a Genetic Template

21.7K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
21.7K
Nucleic acids02:43

Nucleic acids

160.1K
Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
160.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Deep PACBED: Multitask analysis of PACBED images using deep neural networks.

Ultramicroscopy·2026
Same author

Multi-Class Malocclusion Detection on Standardized Intraoral Photographs Using YOLOv11.

Dentistry journal·2026
Same author

The virtual doctor prescribing the future: Diagnostics with interactive clinical decision support.

Computers in biology and medicine·2025
Same author

Data recovery methods for DNA storage based on fountain codes.

Computational and structural biotechnology journal·2024
Same author

RepairNatrix: a Snakemake workflow for processing DNA sequencing data for DNA storage.

Bioinformatics advances·2024
Same author

Nature 4.0: A networked sensor system for integrated biodiversity monitoring.

Global change biology·2024
Same journal

Functional Genomic Evidence for Candidate Small Viral RNA-Mediated Epigenetic Interference in SARS-CoV-1 and SARS-CoV-2.

Computational and structural biotechnology journal·2026
Same journal

From Pixels to Patterns: A Multidimensional Framework to Decode Cytoskeletal Organization.

Computational and structural biotechnology journal·2026
Same journal

A Large Concept Model for Mechanistic Simulation of Disease Trajectories: A Hypothesis-Generating Exemplar for Pediatric Acute Lymphoblastic Leukemia.

Computational and structural biotechnology journal·2026
Same journal

Adversarial Sequence Mutations in AlphaFold and ESMFold Reveal Nonphysical Structural Invariance, Confidence Failures, and Concerns for Protein Design.

Computational and structural biotechnology journal·2026
Same journal

High-Throughput Prediction of Protein-Protein Interactions Uncovers Hidden Molecular Networks in Biosynthetic Gene Clusters.

Computational and structural biotechnology journal·2026
Same journal

A Region-Aware Structured Framework Improves Prediction of Gene Expression from DNA Methylation.

Computational and structural biotechnology journal·2026
查看所有相关文章

相关实验视频

Updated: Jun 7, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

4.1K

优化用于DNA数据存储的源代码.

Peter Michael Schwarz1, Bernd Freisleben1

  • 1Department of Mathematics and Computer Science, University of Marburg, Hans-Meerwein-Str. 6, D-35043, Marburg, Germany.

Computational and structural biotechnology journal
|November 19, 2024
PubMed
概括
此摘要是机器生成的。

优化源代码可以提高DNA数据存储的可靠性和容量. 新型定制的分发功能提高了DNA存储系统的性能,推动了技术的进步.

关键词:
它们是DNA DNA DNA DNA.储存 DNA 储存 DNA 储存喷泉代码 喷泉代码优化优化 优化优化

更多相关视频

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
11:36

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing

Published on: July 3, 2016

10.8K
High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries
11:22

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

Published on: August 12, 2019

18.0K

相关实验视频

Last Updated: Jun 7, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

4.1K
A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
11:36

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing

Published on: July 3, 2016

10.8K
High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries
11:22

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

Published on: August 12, 2019

18.0K

科学领域:

  • 计算机科学 计算机科学
  • 生物工程是生物工程.
  • 信息理论 信息理论

背景情况:

  • 源码对于可靠的数据传输和存储至关重要.
  • 由于其独特的通道特征,DNA数据存储存在独特的挑战.
  • 现有的源代码模型不能完全解决DNA存储道的复杂性.

研究的目的:

  • 优化源代码,以提高DNA数据存储系统的性能.
  • 开发针对DNA存储的喷泉代码分发函数的新型优化算法.
  • 评估这些优化对DNA数据存储的有效性.

主要方法:

  • 开发了适用于喷泉代码的一般优化技术.
  • 提出了创建量身定制的喷泉代码分发函数的新算法.
  • 评估使用DNA存储道特定指标的拟议方法.

主要成果:

  • 优化的源代码显著提高了DNA数据存储的可靠性和容量.
  • 定制的分发功能为DNA数据存储应用提供了新的改进.
  • 开发的方法表明,DNA数据存储的喷泉代码的可用性得到了提高.

结论:

  • 优化源代码对于释放DNA数据存储的全部潜力至关重要.
  • 提出的方法和编码方案代表了重大进步.
  • 开发的方法和方案以开源软件的形式提供.