执行日常认知量表 (ECog-12) 的简短版本,以检测认知障碍
M Manjavong1, A Diaz, M T Ashford
1Rachel L. Nosheny, Ph.D., Assistant Professor, University of California, San Francisco, Department of Psychiatry, San Francisco VA Medical Center, 4150 Clement Street (114M), San Francisco, CA 94121, Tel: 650-468-0619, Fax: 415-668-2864,
The journal of prevention of Alzheimer's disease
|November 19, 2024
概括
在日常认知 (ECog) 12项尺度上,研究合作伙伴的报告比自我报告更好地区分认知障碍. 纳入一个记忆关注问题可以改善自我报告的ECog-12表现,以区分认知状态.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 认知心理学 认知心理学
背景情况:
- 日常认知 (ECog) 12项尺度衡量功能衰退,并将痴呆症与认知正常 (CU) 个体区分开来.
- 基于自我与告知者 (合作伙伴) 报告和不同的评分方法的ECog-12性能变化存在有限的研究.
研究的目的:
- 评估ECog-12尺度在区分认知状态的诊断性能.
- 为了比较自我报告与合作伙伴报告的ECog-12得分的有效性.
- 评估不同评分系统 (数值与分类) 对ECog-12表现的影响.
主要方法:
- 这是一项采用阿尔茨海默氏病神经成像计划 (ADNI) 数据的横截面诊断测试研究.
- 分析ECog-12在区分认知正常 (CU) 个体与认知障碍 (CI) 个体的表现,包括轻度认知障碍 (MCI) 和痴呆症.
- 对自我报告和合作伙伴报告的连续数值和分类 (例如",任何持续拒绝") ECog-12评分方法的评估.
主要成果:
- 合作伙伴报告的ECog-12截止值得分 (1.45) 在区分CU与CI方面显示出更高的准确性 (AUC 0.78) 与自我报告的得分 (1.36,AUC 0.7) 相比.
- 对合作伙伴报告的分类"持续下降"得分产生了0.78的AUC,与数值得分相似.
- 合作伙伴报告的ECog-12与认知障碍的关联性更强 (OR 35.45),而不是自我报告的得分 (OR 8.79).
结论:
- 研究伙伴报告的ECog-12得分在区分认知状态方面比自我报告的得分更有效.
- 伴侣报告的ECog得分较高表明认知障碍的预后风险更高.
- 添加一个记忆关注问题可以提高自我报告的ECog-12表现,突出显示信息者数据在研究和临床环境中的价值.
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