作为PCS构建块的Zwitterionic 2-Phosphaethene-thiolates[LC) P=CS[LC/P) ]+作为PCS构建块 (LC=NHC,LP=PR3) 的使用情况
Philipp Royla1, Kai Schwedtmann1, Rosa M Gomila2
1Faculty of Chemistry and Food Chemistry, Technische Universität Dresden, 01062, Dresden, Germany.
Angewandte Chemie (International ed. in English)
|November 19, 2024
概括
新的zwitterionic化合物[LC) P=CS[LC/P]+,被合成为多功能PCS构建块. 这些化合物使选择性功能化成为可能,并形成新的协调聚合物和异环.
科学领域:
- 有机化学化学 有机化学
- 协调化学 协调化学
- 合成有机化学 合成有机化学
背景情况:
- 具有独特的结合安排的Zwitterionic化合物在合成化学中具有重要意义.
- 开发用于构建复杂分子架构的新型构建块至关重要.
- 探索-碳-硫 (PCS) 基因的反应性为化学合成提供了新的途径.
研究的目的:
- 为了在多克尺度上合成新的zwitterionicPCS化合物,P=CS,在多克尺度上.
- 调查这些化合物的实用性,作为进一步化学转换的多功能构建模块.
- 探索它们的协调化学和形成新型聚合物结构和异环的潜力.
主要方法:
- 多克尺度合成Zwitterionic化合物[LC) P=CSC/P]+ (3+) 通过CS2附加物与特定和N-异环碳前体的反应.
- 3+与电友 (MeOTf) 和核友 (MesMgBr, Ph3PCH2) 的反应来证明功能化.
- 使用AgOTf的协调研究和使用多前体的循环添加反应.
主要成果:
- 成功合成了zwitterionic PCS化合物3的多克合成.
- 在PCS核心的硫和末端证明了选择性功能化.
- 与银一起形成一个前所未有的线性协调聚合物,其中PCS部分作为桥梁连接体.
- 通过循环添加反应合成五个和八个成员的多异环.
- 对导致潜在PCP合成的C-S债券激活的初步证据.
结论:
- 合成的zwitherionic PCS化合物是有价值和多功能的构建模块.
- 这些化合物表现出多样化的反应性,使选择性功能化和复杂结构的构建成为可能.
- 这项研究为协调化学和新型含异环的合成开辟了新的可能性.
关键词:
2 - - 乙烯 - - 硫酸盐的酸.在PCS中使用PCS.建筑物块块块块块块块块块块块块块块块块的建筑物块块块块的建筑物块块块的建筑物块块块的建筑物块块块的建筑物块块块的建筑物块块的建筑物块块的建筑物块块的建筑物是一种的物质.量子化学计算的量子化学计算更多相关视频
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