内源性葡萄糖样-1受体和依赖葡萄糖的胰岛素型多受体信号传递抑制了空气过敏原诱导的天生的气道炎症

Shinji Toki1, Masako Abney1, Jian Zhang1

  • 1Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Allergy
|November 19, 2024
PubMed
概括

通过葡萄糖样-1受体 (GLP-1R) 和依赖葡萄糖的胰岛素型多受体 (GIPR) 途径的联合信号传递对于调节过敏呼吸道炎症至关重要. 它们的缺乏会加剧过敏原诱导的免疫反应,这表明喘的治疗潜力.

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