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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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相关实验视频

Updated: Jun 7, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

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在老年人中甲状腺激素基准间隔.

Xiaodan Zhai, Yongze Li, Xiaochun Teng

    Endocrine connections
    |November 19, 2024
    PubMed
    概括

    甲状腺激素水平自然会随着年龄的增长而变化. 这次审查表明,较高的甲状腺激素值可能适用于诊断老年人亚临床甲状腺功能障碍症.

    科学领域:

    • 老年学是一门学科.
    • 内分泌学 在内分泌学.
    • 甲状腺研究 甲状腺研究

    背景情况:

    • 预计到2050年,全球65岁及以上人口将达到16%.
    • 甲状腺疾病在老年人群中越来越令人担忧.
    • 甲状腺激素 (TSH) 是甲状腺功能的敏感标记物,对于诊断亚临床甲状腺疾病至关重要.

    研究的目的:

    • 审查现有的关于老年人甲状腺激素参考间隔的文献.
    • 探索老年人适应性和病理性甲状腺激素水平变化之间的区别.
    • 在老年人群中为甲状腺功能障碍提供诊断和治疗值的信息.

    主要方法:

    • 对老年人群中甲状腺蛋白参考间隔研究的系统性文献综述.
    • 在老年人中,对促成甲状腺激素水平变化的因素的分析.
    • 对甲状腺功能标志物与年龄相关的变化进行当前研究的综合.

    主要成果:

    • 在老年人中,甲状腺激素水平可能稍微升高.
    • 在老年人群中观察到甲状腺激素参考间隔的较高上限.
    • 人口异质性可能导致报道的甲状腺激素范围的广泛变化.
    关键词:
    甲状腺功能低下症 甲状腺功能低下症年龄较大的成年人.参考时间间隔是参考时间间隔.甲状腺增生蛋白 甲状腺增生蛋白

    更多相关视频

    Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
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    Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

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    Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
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    Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

    Published on: October 6, 2023

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    Last Updated: Jun 7, 2025

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
    04:39

    Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

    Published on: March 17, 2023

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    Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
    07:30

    Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

    Published on: May 10, 2018

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    Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
    04:14

    Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

    Published on: October 6, 2023

    771

    结论:

    • 甲状腺激素与年龄相关的变化需要重新评估诊断标准.
    • 在老年人中诊断亚临床甲状腺功能低下症时,较高的甲状腺激素值似乎是合理的.
    • 需要进行进一步的研究,以建立精确的,针对年龄的甲状腺增生蛋白的参考间隔.