在模拟的深海超临界二氧化碳-水两相环境中,预微生物核酸化
Shotaro Tagawa1,2,3, Ryota Hatami4,5, Kohei Morino1,2
1Earth-Life Science Institute, Institute of Science Tokyo, Tokyo, Japan.
Astrobiology
|November 19, 2024
概括
超临界的二氧化碳 (ScCO2) 和水环境促进了前生物核酸合成. 这种深海条件模仿了湿干循环,使得早期生命中必不可少的有机分子形成.
科学领域:
- 天体生物学 天体生物学
- 地质化学 地质化学
- 有机化学 有机化学
背景情况:
- 在富含水的环境中,复杂有机分子的前生物合成仍然是一个重大挑战.
- 深海的热水喷口显示出液态二氧化碳 (CO2) 排放,这表明地CO2池.
- 一个最近的假设提出,一个二相超临界CO2 (ScCO2) -水环境促进有效的有机脱水和凝结.
研究的目的:
- 实验验证一个二相ScCO2-水环境可以驱动益生菌核酸合成的假设.
- 调查ScCO2在促进脱水和凝结反应中的作用,这对生命早期化学至关重要.
- 评估深海二氧化碳池作为 prebiotic 有机合成环境的潜力.
主要方法:
- 在ScCO2-水双相条件下,在水热反应器中进行核酸酸化反应.
- 使用玻璃窗反应器直接观察二相环境和水气相互作用.
- 在完全含水的环境中进行了对照实验,没有ScCO2.
主要成果:
- 在68.9°C下120小时后,氨酸,氨酸,关氨酸和腺氨酸的酸化产生了核酸单酸盐 (NMP),核酸二酸盐和碳酸核酸.
- 添加尿素增强了化物种的产生,5'-NMP的产量超过10%.
- 在没有ScCO2的情况下,酸化没有发生,并且观察到水逃入ScCO2阶段,模仿湿干循环.
结论:
- 这种ScCO2-水双相环境有效地驱动了益生菌核酸合成,类似于陆地温泉湿干循环.
- 水相中的高酸度有助于通过从矿物中释放正酸盐来促进核酸合成.
- 深海的二氧化碳池为地球和潜在的海洋世界上的前生物核酸合成和其他凝结反应提供了可行的环境.
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