在21118名患者的非选择性腹部和胸腔腹部CT扫描中发现间歇性肺异常
Nicola Sverzellati1, Gianluca Milanese1, Christopher J Ryerson1
1From the Scienze Radiologiche, Department of Medicine and Surgery, University of Parma, Parma, Italy (N.S., G.M., V.R.P., S.E.G., E.B., F.S., C.M., F.M., R.E.L., M.S.); Department of Medicine, University of British Columbia and Center for Heart Lung Innovation, St Paul's Hospital, Vancouver, Canada (C.J.R.); Department of Radiology, Brigham and Women's Hospital, Boston, Mass (H.H.); National Heart and Lung Institute, Imperial College London, London, England (S.L.F.W.); and University Hospital of Parma, Parma, Italy (E.I.).
间歇性肺异常 (ILAs) 影响1.7%的接受CT扫描的患者,近一半没有报告. 这些发现,特别是纤维化ILA,与死亡风险增加有关.
科学领域:
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
- 医疗成像医学成像
背景情况:
- 间歇性肺部异常 (ILAs) 是间歇性肺部疾病的早期指标,在CT扫描中偶然发现.
- 在未经选择的,常规的临床环境中,关于ILA患病率的数据有限.
研究的目的:
- 在未经选择的患者群体中确定腹部或胸腔腹部CT扫描上ILAs的患病率.
- 评估这些ILA的报告不足率和潜在的临床影响.
主要方法:
- 从2008年至2015年间从未选择的患者 (≥50岁) 进行连续腹部或胸腔腹部CT扫描的回顾性审查.
- 将CT结果与原始临床报告进行比较,以确定报告不足.
- 使用多变量模型分析与ILA进展和死亡率相关的因素.
主要成果:
- 在21,118名患者中,ILA在1.7%的患者中被发现,有1.0%的患者有纤维性特征.
- 报告不足是显著的,在原始报告中,43.9%的ILA被遗漏.
- 引支气管切除指数预测了ILA的进展,而纤维化的ILA增加了呼吸道死亡风险的四倍.
结论:
- 在接受CT的广泛,未经选择的患者队列中,ILA的患病率为1.7%.
- 尽管与死亡风险增加有关,但很大一部分ILA的报告不足.
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