从头部和部状细胞癌的远程转移的现代管理
Patrick Bradley1, Claudia Montenegro2,3, Cesare Piazza2,3
1Department of Otolaryngology - Head and Neck Surgery, Nottingham University Hospitals, Queens Medical Centre Campus, Nottingham, UK.
Current opinion in otolaryngology & head and neck surgery
|November 19, 2024
概括
在头角状细胞癌 (HNSCC) 中,远程转移显著降低了存活率. 管理因转移程度而异,用于小转移性疾病的手术/放射治疗和用于多转移性病例的全身疗法.
科学领域:
- 在瘤学瘤学.
- 头部和部癌症研究研究
- 转移研究 转移研究
背景情况:
- 远程转移发生在4-26%的头角状细胞癌 (HNSCC) 患者中.
- 转移意味着疾病已晚期,严重降低了生存率.
- 治疗需要适应转移负担的多学科方法.
研究的目的:
- 为了提供一个全面的,最新的概述管理远程转移在HNSCC.
- 审查目前转移性HNSCC的诊断和治疗策略.
- 综合证据证明转移模式对HNSCC结果的影响.
主要方法:
- 现有文献的叙述性审查.
- 对远程转移的诊断和分期技术的分析.
- 对寡头转移性和多转移性HNSCC的治疗方式的评估.
主要成果:
- 准确的检测和分期对于预后和治疗指导至关重要.
- 低基质 HNSCC (最多 5 个转移) 可能通过手术或立体体射线疗法治愈.
- 多转移性HNSCC通常需要全身疗法 (化疗,向疗法) 或最佳支持性护理.
- 很少,头部和部区域可能是其他癌症的遥远转移的地点.
结论:
- 远程转移是HNSCC的生存的一个关键决定因素.
- 远程转移的模式与生存结果相关.
- 对于患有HNSCC远程转移的患者来说,个性化,多学科的治疗选择至关重要.
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