低垂体和COVID-19之间的关系
Giulia Carosi1, Arianna Cremaschi1, Claudia Giavoli1,2
1Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Pituitary
|November 19, 2024
概括
COVID-19可能会导致下垂体,一种影响下垂体的疾病. 现有下垂体病患者面临COVID-19风险增加,需要治疗调整和对长期垂体功能的进一步研究.
科学领域:
- 内分泌学 在内分泌学.
- 病毒学 病毒学
- 内部医学 内部医学
背景情况:
- 随着COVID-19的流行,人们对其对内分泌系统的影响产生了担忧.
- 缺陷垂体激素生产的状况 - - 低垂体症正在与SARS-CoV-2感染有关的越来越多的研究中.
研究的目的:
- 审查当前关于下垂体和COVID-19的研究.
- 为了检查病毒对垂体腺的影响和荷尔蒙缺乏症患者的结果.
主要方法:
- 使用PubMed进行了一项文献审查.
- 搜索术语包括"COVID19"",下垂体"和"下垂体主义".
主要成果:
- 研究表明,COVID-19患者的脑下垂体功能受损多种,原因不明 (病毒损伤与炎症).
- 下垂体缺陷可能在感染后持续存在,可能导致长期COVID.
- 患有下垂体病的患者可能面临更高的COVID-19感染,并发症和死亡风险.
结论:
- COVID-19在急性感染和恢复期间会影响内分泌系统.
- 低位症可能是SARS-CoV-2感染的结果,现有的低位症会增加患者的风险.
- 在COVID-19后对垂体功能的长期随访数据至关重要,患者需要管理替代疗法的指导.
相关概念视频
Major Hormones and Their Functions
333
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
333
Hypothalamic-Pituitary Axis
59.3K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
59.3K
The Pituitary Gland
6.4K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
6.4K
Hypoglycemia and Glucagon
152
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
152
Adrenal Gland Disorders
1.3K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
1.3K
Hormones of the Pituitary Gland
6.3K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
6.3K


