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Updated: Jun 7, 2025

Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis
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Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis

Published on: July 16, 2021

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开发和验证一种基于FEZF2的新型光传递器,用于皮质脊髓运动神经元

Ronghua Wu1, Skandha Ramakrishnan2, Haixu Lin1

  • 1Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, 19 Qixiu Road, Nantong, 226001, Jiangsu, China.

Metabolic brain disease
|November 19, 2024
PubMed
概括

研究人员开发了一种新的光记者,专门标记活体皮质脊髓运动神经元 (CSMNs). 该工具有助于研究影响自愿运动和CSMN功能的神经退行性疾病.

关键词:
皮层脊柱运动神经元在Fezf2中,我们可以使用Fezf2 .光灯记者 光灯记者遗传性缩性残症是一种遗传性残症.林氏病毒 (Lentivirus) 是一种隐形病毒.

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Construction of Cell-based Neurotransmitter Fluorescent Engineered Reporters CNiFERs for Optical Detection of Neurotransmitters In Vivo

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相关概念视频

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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