早期乳腺癌携带生殖系BRCA1/2突变的患者中,人环素诱导的心脏毒性:BRCAN研究

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Alfonso Cortés-Salgado1, Juan José Serrano2, David Cordero Pereda3

  • 1Medical Oncology Department, Hospital Universitario Ramón y Cajal (IRYCIS), 28034 Madrid, Spain.

The oncologist
|November 19, 2024
PubMed
概括

与非携带者相比,患有生殖系BRCA1/2突变 (gBRCA1/2m) 的患者在接受 antracycline 化疗后,左心室射出分数 (LVEF) 的减少更大. 这表明gBRCA1/2m患者在癌症治疗期间可能需要更密切的心脏监测.

关键词:
这就是BRCA1/2的原因.这种类型的抗生素是Anthracyclines.乳腺癌 乳腺癌 乳腺癌心脏瘤学心脏瘤学心脏有毒性心脏有毒性

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