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Updated: Jun 7, 2025

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胆固醇结合弹性类似重组剂:分子动力学模拟,形状变化和生物活性

Rui R Costa1,2,3, Vicente Domínguez-Arca4,5, Brenda Velasco3

  • 13B's Research Group, I3Bs─Research Institute on Biomaterials, Biodegradables, and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-694 Barco, Guimarães, Portugal.

ACS applied materials & interfaces
|November 19, 2024
PubMed
概括

弹性样重组酶 (ELR) 的胆固醇功能化改善了它们的自我组装和与脂质双层的相互作用. 这为增强的纳米颗粒药物递送系统创造了新的生物材料.

关键词:
格罗马克斯计算机模拟胆固醇 胆固醇 胆固醇 是一种与弹性素类似的重组聚合物.自动组装的自动组装机刺激反应的生物材料

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The Equilibrium Binding Constant and Binding Strength02:18

The Equilibrium Binding Constant and Binding Strength

The equilibrium binding constant (Kb) quantifies the strength of a protein-ligand interaction. Kb can be calculated as follows when the reaction is at equilibrium:
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