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Updated: Jun 7, 2025

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RAD52和ERCC6L/PICH在线粒分裂中对基因组稳定性具有补偿关系

Beth Osia1, Arianna Merkell1, Felicia Wednesday Lopezcolorado1

  • 1Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, California, United States of America.

PLoS genetics
|November 19, 2024
PubMed
概括

RAD52和ERCC6L是DNA修复因子,在线粒分裂过程中保护基因组稳定性. 它们的缺乏导致DNA损伤增加,这表明它们共同补偿以保持基因组完整性.

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