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有条件激活的瘤特异性膜蛋白降解基因

Hongxiang Liu1, Zhijiang Fu1, Yu Han1,2,3

  • 1Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen 518055, China.

Journal of the American Chemical Society
|November 19, 2024
PubMed
概括

这项研究引入了一种针对细胞表面蛋白质的新型条件激活膜蛋白降解剂 (Pro-MPD). 支持MPD的药物通过仅在瘤部位激活来降低毒性,

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